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Pramo Molecular

Lupe

Delivering Nucleic Acid Drugs

Team:
Merle Fuchs
(PhD, Dipl. Biol. Molecular Biology)
Project Management, Strategic Planning, Financing

Mona Fechler Bitteti
(M.Sc. Molecular Biology)
Quality Control

Ida Shaef
(M.Sc. Biological Chemistry)
Leader 3D Organ Models

Thomas Hiller
(PhD, M.Sc. Biotechnology)
Technical Leader

Sector:
Biotechnology/Pharma

Mentor:
Prof. Jens Kurreck, PhD, Applied Biochemistry

Faculty:
Faculty III - Process Sciences
Institute of Biotechnology
Department of Applied Biochemistry

Support:
EXIST-Forschungstransfer: 10.2019 – 09.2020

Delivery systems for nucleic acid based drugs

Lupe

Our idea

Pramo Molecular ("pramo" = "ferry" in Esperanto), develops covalently bound carrier molecules that transport therapeutic oligonucleotides like siRNA or antisense DNA into the target cells in a particularly efficient and compatible manner.

Transport problems across lipid membranes have prevented the use of nucleic acid agents to treat serious infectious, metabolic or cancer diseases. Pramo Molecular´s delivery molecules are particularly easy to manufacture in compliance with pharmaceuticals.

During our preclinical development we are also using humanized and murine 3D tissue models to limit animal testing.

www.pramo-molecular.org

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